TY  - JOUR
T1  - Effectiveness of Gaseous Ozone as a Disinfectant for Nosocomial Pathogens in a Healthcare Emergency Room
A1  - Mohammed Ali Alshehri
A1  - Fayez Saeed Bahwerth
A1  - Zaher Ahmed Althagafi
A1  - Hassan Abdullah Alsolami
A1  - Ahmad Musa Almalki
A1  - Ahmed Saif
A1  - Sattam Almalki
A1  - Abdulbari Abdulwahab Mazhar
A1  - Mohammed Ahmed Alghamdi
A1  - Ahmad Farouk
A1  - Riham SadiqAshari
A1  - Samer Mohammad Yousr
A1  - Bandar Abdallah Bahwny
A1  - Haitham Mohammad Al-Afghani
A1  - Hamza Mohammad Assaggaf
A1  - Riyadh Hussain Aeban
A1  - Omar Bashir Ahmed
A1  - Hani Mohammad Al-Afghani
JF  - Archives of Pharmacy Practice
JO  - Arch Pharm Pract
SN  - 2320-5210
Y1  - 2021
VL  - 12
IS  - 4
DO  - 10.51847/UvHgz7UtJC
SP  - 17
EP  - 24
N2  - Nosocomial infections are frequently caused by bacteria that are resistant to various antibiotics, resulting in the mortality or delayed recovery of hospitalized patients. Several studies have investigated the efficiency of ozone (O3) gas for the disinfection of surfaces to eliminate different nosocomial pathogens. In this study, the efficacy of O3 gas in a heavily contaminated healthcare facility was investigated using a low concentration of FDA-approved and human-safe O3. The total microbial loads on the air conditioning (AC) duct, wall, and tables after 1 month of O3 application were 0 CFU/100 cm2, 1 CFU/ 100 cm2, and 1 CFU/100 cm2, respectively. Moreover, the total microbial loads on the AC duct, wall, and tables 2 months after O3 application were 0 CFU/m2, 14 CFU/m2, and 1 CFU/m2, respectively. Finally, after the third month following O3 application, the microbial loads were 0 CFU/100 cm2 on the AC duct, 7 CFU/100 cm2 on the walls, and 54 CFU/100 cm2on the tables. Overall results show that O3 gas controlled fungal growth, as it was decreased to minimal levels on some swabbed surfaces or even eliminated on most swabbed medical devices and work surfaces. Moreover, O3 is capable of eradicating nosocomial pathogens present in hidden areas even at low concentrations that match the levels approved by the FDA for human exposure. The study concluded that gaseous O3 can serve as an effective, safe, and cheap disinfectant. O3 could effectively work to eliminate both nosocomial bacteria and mould pathogens. 
UR  - https://archivepp.com/article/effectiveness-of-gaseous-ozone-as-a-disinfectant-for-nosocomial-pathogens-in-a-healthcare-emergency-xhdxfn5nm3xb8al
ER  -