TY  - JOUR
T1  - Evaluating the Association of Red Blood Cell Parameters and Glycemic Control in Type 2 Diabetic Patients at Tien Giang General Hospital
A1  - Tram Van Ta
A1  - Huyen Bich Thi Nguyen
A1  - Hai Thanh Tran
A1  - Hien The Pham
JF  - Archives of Pharmacy Practice
JO  - Arch Pharm Pract
SN  - 2320-5210
Y1  - 2019
VL  - 10
IS  - 4
SP  - 153
EP  - 159
N2  - Background: Red blood cell distribution width (RDW), a hematologic index, is a quantitative measure of the range in volume and size of red blood cells. Hyperglycemia in patients with type 2 diabetes is considered to promote the formation of glycosylated hemoglobin (HbA1C) and to shorten the lifespan of red blood cells by reducing their deformability and increasing their osmotic fragility and adhesiveness. Objectives: To evaluate the association between red cell distribution width (RDW), mean corpuscular volume (MCV), and mean corpuscular hemoglobin content (MCHC) of red blood cells and glycemic control in patients with type 2 diabetes. Methods: This retrospective study included 107 patients with type 2 diabetes who were undergoing treatment at Tien Giang General Hospital from April to August 2019. Gender, age, complete blood count, plasma glucose, HbA1C, cholesterol, and triglyceride data were collected. The patients were divided into two groups: group I (HbA1C≤6.5–6.9%; n=51) and group II (HbA1C≥7.0%; n=56). Results: RWD was 13.32 for the group I and 13.95 for group II. MCHC was 32.21 for the group I and 32.84 for group II. RDW and MCHC were significantly higher in patients without good glycemic control (HbA1C≥7.0%) than with good HbA1C control (6.5–6.9%). RDW showed a significant correlation between glucose concentration and MCHC. HbA1C and MCHC were also significantly correlated. Conclusion: Good glycemic control is associated with lower RDW and MHC values in patients with type 2 diabetes. Therefore, RDW and MCHC can be used as prognostic markers to assist in blood glucose control in these patients.
UR  - https://archivepp.com/article/evaluating-the-association-of-red-blood-cell-parameters-and-glycemic-control-in-type-2-diabetic-patients-at-tien-giang-general-hospital
ER  -