%0 Journal Article
%T High Levels of Blood Lactate Associated with the Use of Low Dose Aspirin: A Case-Control Study
%A Carina Bona
%A Roberto Lozano
%J Archives of Pharmacy Practice
%@ 2320-5210
%D 2024
%V 15
%N 3
%R 10.51847/Nu1RwJxUns
%P 10-12
%X We evaluate the risk of severe hyperlactatemia (LA) >4 in patients on chronic treatment with low doses of aspirin (ASP) and estimate the magnitude of the association. For this, a case-crossover study design, where patients who have experienced the outcome (cases) are a part of their controls by containing a period before the onset of the outcome. Additionally, a design based on person-day measurements, rather than individuals, was used for cases and controls. When comparing the group of cases (exposed to ASP/not exposed), we found: 127/578 vs. group controls (ASP exposed/unexposed): 547/3,968, and an OR=1.6 (95% CI:1.29) was obtained (-1.97; z= 4.31; p
%U https://archivepp.com/article/high-levels-of-blood-lactate-associated-with-the-use-of-low-dose-aspirin-a-case-control-study-am6tsceddr5zz3r