TY  - JOUR
T1  - Investigation of Wound Healing Properties of Aqueous Extracts of Caucasus Herbs at Diabetes Mellitus
A1  - Alexandra Sergeevna Tsiganock
A1  - Anastasiia Evgenevna Bgantseva
A1  - Viktoria Romanovna Vostrikova
A1  - Daniil Sergeevich Shevel
A1  - Azman Ilesovna Saidarova
A1  - Ilishan Magamedovich Bekbuzarov
A1  - Tagir Kurbanovich Kurbanov
A1  - Saida Muradinovna Shadova
JF  - Archives of Pharmacy Practice
JO  - Arch Pharm Pract
SN  - 2320-5210
Y1  - 2024
VL  - 15
IS  - 4
DO  - 10.51847/J9Uuh2bq3a
SP  - 39
EP  - 44
N2  - Today, diabetes mellitus is one of the most common pathologies that leads to severe systemic complications. In this article, we studied the regenerative processes of an infected wound in hyperglycemia using dosage forms based on plant raw materials Acacia nilotica, Cyperus rotundus, Trigonella foenumgraecum, and Cymbopogon proximus. A model of dexamethasone-induced hyperglycemia was experimentally reproduced, followed by the creation of a wound and double application of Streptococcus epidermidis-infected material from a patient with streptoderma to the wound area. During the study, we found that the use of aqueous emulsions containing Acacia nilotica, Trigonella foenumgraecum, Cyperus rotundus, and Cymbopogon proximus has a positive effect on dysmetabolic disorders that occur during experimental dexamethasone-induced hyperglycemia (activity of hepatic transaminases decreases, blood glucose levels normalize), peripheral blood composition is optimized (the level of erythrocytes and hemoglobin, leukopenia is leveled). Such shifts create a favorable background for the course of reparative processes against the background of dexamethasone-induced damage, which inhibits the course of regenerative processes. 
UR  - https://archivepp.com/article/investigation-of-wound-healing-properties-of-aqueous-extracts-of-caucasus-herbs-at-diabetes-mellitus-fexdjmevvowseif
ER  -