TY  - JOUR
T1  - The Role and Pathogenetic Mechanisms of Long Non-Coding RNAs in Liver Fibrosis
A1  - Denis Sergeevich Shpakov
A1  - Marianna Evgenevna Romas
A1  - Alena Gochaevna Margieva
A1  - Milana Evgenievna Brovkina
A1  - Ellina Borisovna Khabieva
A1  - Sofya Ruslanovna Mutalieva
JF  - Archives of Pharmacy Practice
JO  - Arch Pharm Pract
SN  - 2320-5210
Y1  - 2023
VL  - 14
IS  - 3
DO  - 10.51847/5YE2FxmN9M
SP  - 7
EP  - 9
N2  - Liver fibrosis is a serious disease characterized by the excessive formation of connective tissue in an organ with a predisposition to cirrhosis. Understanding the mechanisms underlying the development of liver fibrosis is an important step towards the development of new methods for the diagnosis and treatment of this disease. Long non-coding RNAs (lncRNAs) are a class of RNAs that have been shown to play an important role in the pathogenesis of liver fibrosis and may be potential targets for new therapeutic approaches. This article reviews the role and pathogenetic mechanisms of lncRNAs in liver fibrosis, studies related to the identification of these mechanisms, as well as the prospects for using lncRNAs as diagnostic markers and therapeutic targets. The identification and study of these lncRNAs may provide new opportunities for the development of innovative approaches to the diagnosis and treatment of liver fibrosis. Further research is needed to fully understand the molecular mechanisms associated with lncRNAs and liver fibrosis and to determine their potential as biomarkers and therapeutic targets. 
UR  - https://archivepp.com/article/the-role-and-pathogenetic-mechanisms-of-long-non-coding-rnas-in-liver-fibrosis-ohrnmyfknxac1kj
ER  -