The ultimate goal of endodontic treatment is either to prevent the development of apical periodontitis or to create adequate conditions for periapical healing in the presence of disease. Commiphora molmol has also been investigated for its antibacterial activity. It is another type of naturally occurring plant extract that has shown a significant effect on reducing bacterial infection. Enterococcus faecalis is a gram-positive facultative anaerobe. It is found in 4–40% of primary endodontic infections. The frequency of E. faecalis found in persistent periradicular lesions is much higher. In fact, failed root canal treatment cases are nine times more likely to contain E. faecalis than primary endodontic infections. Thus, the rationale of endodontic treatment is to eradicate the infection present and/or prevent the microorganisms from infecting or re-infecting the root canal system. A (Green tea, Zingiber Officinale, Commiphora Molmol (Myrrh) were prepared using the agar plates. Cultures of E. faecalis were grown in agar. We compared 5% NaOCl (sodium hypochlorite irrigation agent) as a control group with three sample groups. There was no statistically significant difference between the zone of inhibition of sodium hypochlorite and green tea (p-value: 0.855), Commiphora Molmol (p-value: 0.639). However, there was significant difference between the NaOCl and Ginger group (p-value: 0.000). Overall, no significant comparison could be achieved when comparing the herbal extracts with sodium hypochlorite. Future studies can be much more useful if the combination of these herbal extracts can be tested for their efficacy.