Chronic diarrhea is a symptom of the inflammatory condition known as microscopic colitis (MC) a microscope showing signs of persistent inflammation but with normal colonic morphology under a microscope. The study looked at how common CD was among MC patients, various characteristics of these 2 ailments, as well as the possible association between CD and MC with its two types by analyzing previously available literature. The papers were selected using the EBSCO Information Services and the PubMed database. All essential articles pertaining to both our topics Several more works were consulted for this evaluation. Not included were any other articles that are unrelated to this topic. The group members examined the data that had been extracted in a specific format. both MC types have a sizable CD frequency, this comprehensive Analysis shows that CD and MC have a statistically significant association with an elevated risk of current and past MC in CD patients. When assessing patients with any condition, GI specialists should be cautious of this relationship.