<!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Archiving and Interchange DTD with MathML3 v1.3 20210610//EN" "JATS-archivearticle1-3-mathml3.dtd"><article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink"
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  <front>
    <journal-meta>
      <journal-id journal-id-type="iso-abbrev">Arch Pharm Pract</journal-id>
      <journal-id journal-id-type="publisher-id">archivepp.com</journal-id>
      <journal-id journal-id-type="publisher-id">Arch Pharm Pract</journal-id>
      <journal-title-group>
        <journal-title>Archives of Pharmacy Practice</journal-title>
      </journal-title-group>
      <issn pub-type="epub">2320-5210</issn>
    </journal-meta>
    <article-meta>
      <article-id pub-id-type="publisher-id">archivepp.com-1161</article-id>
      <article-id pub-id-type="doi">10.51847/OphHf7XuDm</article-id>
      <article-categories>
        <subj-group subj-group-type="heading">
          <subject>Original research</subject>
        </subj-group>
      </article-categories>
      <title-group>
        <article-title>Cognitive Disorders Around Surgery and Its Prevention Strategies</article-title>
      </title-group>
                    <contrib-group>
                      <contrib contrib-type="author">
              <name>
                <surname>Noor</surname>
                <given-names>Hassan</given-names>
              </name>
                              <xref rid="aff1" ref-type="aff">1</xref>
                              <xref rid="aff2" ref-type="aff">2</xref>
                                        </contrib>
                      <contrib contrib-type="author">
              <name>
                <surname>Coțe</surname>
                <given-names>Adrian</given-names>
              </name>
                              <xref rid="aff3" ref-type="aff">3</xref>
                                                            <xref rid="cor1" ref-type="corresp" />
                          </contrib>
                      <contrib contrib-type="author">
              <name>
                <surname>Micu</surname>
                <given-names>Alexandra</given-names>
              </name>
                              <xref rid="aff2" ref-type="aff">2</xref>
                                        </contrib>
                      <contrib contrib-type="author">
              <name>
                <surname>Pirvut</surname>
                <given-names>Valentin</given-names>
              </name>
                              <xref rid="aff1" ref-type="aff">1</xref>
                              <xref rid="aff2" ref-type="aff">2</xref>
                                        </contrib>
                  </contrib-group>
                  <aff id="aff1">
            <label>1</label>Department of Medicine, Faculty of Medicine, “Lucian Blaga” University, Sibiu, Romania.
          </aff>
                  <aff id="aff2">
            <label>2</label>Hospital Medlife-Polisano, Sibiu, Romania.
          </aff>
                  <aff id="aff3">
            <label>3</label>Department of Surgical Discipline, Faculty of Medicine and Pharmacy, University of Oradea, 410087 Oradea, Romania.
          </aff>
                          <author-notes>
            <corresp id="cor1">
              <bold>Address for correspondence:</bold> Prof. Wael Abu Dayyih, Department of
              Pharmaceutical Chemistry, Faculty of Pharmacy, Mutah University, Al-Karak 61710, Jordan.
                              E-mail: <email xlink:href="Adrian.cote@gmail.com">Adrian.cote@gmail.com</email>
                          </corresp>
          </author-notes>
                    <pub-date pub-type="epub">
        <day>27</day>
        <month>01</month>
        <year>2024</year>
      </pub-date>
      <volume>15</volume>
      <issue>1</issue>
      <fpage>33</fpage>
      <lpage>39</lpage>
      <permissions>
        <copyright-statement>
          Copyright: &#x000a9; 2026 Archives of Pharmacy Practice
        </copyright-statement>
        <copyright-year>2026</copyright-year>
        <license>
          <ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/"
            specific-use="textmining" content-type="ccbyncsalicense">
            https://creativecommons.org/licenses/by-nc-sa/4.0/</ali:license_ref>
          <license-p>This is an open access journal, and articles are distributed under the terms of
            the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows
            others to remix, tweak, and build upon the work non-commercially, as long as appropriate
            credit is given and the new creations are licensed under the identical terms.</license-p>
        </license>
      </permissions>
      <abstract>
        <title>A<sc>BSTRACT</sc></title>
        <p>One of the important complications related to surgery and anesthesia is cognitive disorders, it is necessary to think about such complications before the surgery and anesthesia and put the necessary preparations on the agenda. Lack of accuracy and lack of awareness of the factors that cause these problems can be the main cause of these problems. The purpose of this review article is to examine the causes and factors that cause cognitive problems around surgery so that by providing solutions, they can be prevented from spreading and appearing after surgery. In this study, various appropriate articles related to the topic were used, which were published between 1990 and 2022 in the field of causes of cognitive problems and prevention strategies. References for this review article are from Google Scholar, PubMed, and Science Direct were obtained. The authors used keywords including cognitive problems, psychological problems during anesthesia, after anesthesia, and surgery in these sites. In this study, the things that should be considered in anesthesia and surgery to prevent the occurrence of cognitive problems were investigated. These include: the use of neuroprotectants, psychoactive drugs, anticholinergic system, anesthesia depth, pediatrics and occurrence of problems, circadian and sleep disorders, patient privacy, blood sugar, patient&amp;#39;s spiritual rituals, hemoglobin, electrolytes, blood pressure, capnography and oxygenation, patient position and posture, emboli, drug interactions, cardiac function, platelet activity, stress and pain, hypothermia and hyperthermia, delay in discharge, ileus and antibiotics.</p>
      </abstract>
      <kwd-group>
                <kwd>Cognitive disorders</kwd>
                <kwd>Surgery</kwd>
                <kwd>Cognitive problems</kwd>
                <kwd>Psychological problems</kwd>
                <kwd>Anesthesia</kwd>
              </kwd-group>
    </article-meta>
  </front>
</article>