The increasing resistance of cancers to common treatments has caused researchers to make more efforts to discover and identify new anticancer agents. Excessive use of chemical drugs increases the resistance of cancer cells, and as a result, treatment measures fail due to a decrease in the response level of these cells to the drug. Therefore, it is extremely important to study drugs that are more effective and have fewer side effects. Angiogenesis is a new treatment method that has been studied recently due to the high importance of this treatment method and the efficiency of this method in the treatment of some diseases, including all types of tumors. There are many hopes for the use of this method. It has created an effective method. Among the most important potential advantages of this method in cancer treatment, we can mention the absence of cell resistance problems, easy access to intravascular targets, as well as the wide scope of using this type of strategy to treat many types of diseases related to angiogenesis. Therefore, the use of different angiogenesis models and the development of these models can be very important for the treatment of all types of cancer and other diseases. In this review article, various dimensions of the angiogenesis process and the mechanisms and factors related to it, as well as the studies surrounding them, have been discussed.