Phytotherapy is the treatment and prevention of diseases using plants, plants part such as herbal, flowers, leaves, peels, and roots or mixtures of them. This study seeks to determine the impact of moringa on biochemical and immunological alterations in hyperglycemic rats. Moringa is one of the most herbal plants with remarkable medicinal effects, including treating high blood sugar and enhancing immune functions. Twenty-four (24) male albino Sprague-Dawley strain rats were separated into four groups, with one serving as the negative control group (normal); the other groups were used to induce diabetes with alloxan. The rats were ten weeks old and weighed 15010g. Two of the diabetes groups received 5% 10% Moringa for 28 days, while the positive control group of one was given a conventional diet. After the experiment, a blood sample was obtained, and the organs were taken out and biochemically analyzed. Therefore, when compared to the control (+) group, all experimental groups exhibited significantly different glucose levels. In addition, when compared to the control (+) group, group 4 (10% Moringa) had the best effects on the triglycerides, HDL, and LDL of the diabetic rats. In diabetic rats, ALP, AST, ALT, and uric acid were best measured in Group 3 (5% Moringa), while urea and creatinine were best measured in Group 4 (10% Moringa). Even when measured against the reference (+) group. This study suggested giving diabetics varying doses of moringa, as well as perhaps giving them varied doses of moringa to lower LDL and atherogenic index readings.