Covid-19 is a serious virus related to severe illness courses. The main complication of this virus is venous thromboembolism which includes pulmonary embolism and deep vein thrombosis. Doppler ultrasound is becoming increasingly accepted as an accurate, non-invasive modality of imaging in suspected DVT. To evaluate the prevalence of DVT using Doppler sonography among COVID-19 patients concerning clinical and laboratory findings at Taif City, Saudi Arabia, and to determine the D-dimer elevation in DVTs patients and its association with the high-altitude regions. This is a retrospective study conducted at King Faisal Hospital, Taif. Including 150 Patients. Lower limb Doppler ultrasound was performed on all patients admitted either to the ward or intensive care unit between April to December 2021. Clinical and laboratory features, thrombotic complications, and outcomes were assessed.150 patients were screened in this study including 96 female and 54 male. DVT was found in 86 patients (57.3%) while those who didn't complain of DVT represented (42.7%). The mean age was (>64) years, and most of the respondents were inpatients (70.0%), while Isolation, ICU, and ER accounted represented (12.7%, 11.3%, and 6.0%) respectively. Also, (54.7%) of patients who complained of DVT had an increase in D-dimer values, compared to inpatients that didn't complain of DVT. Ultrasound is a helpful tool for detecting DVT in COVID-19 patients., based on the large percentage of people with venous thrombosis. Also, this study proved that there is a statistically significant association between DVT and elevated D-dimer among confirmed COVID-19 patients who live in Taif City.