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  <front>
    <journal-meta>
      <journal-id journal-id-type="iso-abbrev">Arch Pharm Pract</journal-id>
      <journal-id journal-id-type="publisher-id">archivepp.com</journal-id>
      <journal-id journal-id-type="publisher-id">Arch Pharm Pract</journal-id>
      <journal-title-group>
        <journal-title>Archives of Pharmacy Practice</journal-title>
      </journal-title-group>
      <issn pub-type="epub">2320-5210</issn>
    </journal-meta>
    <article-meta>
      <article-id pub-id-type="publisher-id">archivepp.com-1248</article-id>
      <article-id pub-id-type="doi">10.51847/ng72yn5h2b</article-id>
      <article-categories>
        <subj-group subj-group-type="heading">
          <subject>Original research</subject>
        </subj-group>
      </article-categories>
      <title-group>
        <article-title>Reimagining the Pharmacy Workbench as a Human–AI Coordination Space for Medication Decisions</article-title>
      </title-group>
                    <contrib-group>
                      <contrib contrib-type="author">
              <name>
                <surname>Anderson</surname>
                <given-names>James</given-names>
              </name>
                              <xref rid="aff1" ref-type="aff">1</xref>
                                        </contrib>
                      <contrib contrib-type="author">
              <name>
                <surname>Rossi</surname>
                <given-names>Maria</given-names>
              </name>
                              <xref rid="aff2" ref-type="aff">2</xref>
                                                            <xref rid="cor1" ref-type="corresp" />
                          </contrib>
                      <contrib contrib-type="author">
              <name>
                <surname>Clark</surname>
                <given-names>William</given-names>
              </name>
                              <xref rid="aff3" ref-type="aff">3</xref>
                                        </contrib>
                  </contrib-group>
                  <aff id="aff1">
            <label>1</label>Department of Human-AI Coordination in Pharmacy, Faculty of Pharmacy, University of Manchester, Manchester, United Kingdom.
          </aff>
                  <aff id="aff2">
            <label>2</label>Department of Pharmacy Informatics and Decision Support, Faculty of Pharmacy, University of Milan, Milan, Italy.
          </aff>
                  <aff id="aff3">
            <label>3</label>Department of Digital Health and Clinical Workflow, Faculty of Pharmacy, University of Melbourne, Melbourne, Australia.
          </aff>
                          <author-notes>
            <corresp id="cor1">
              <bold>Address for correspondence:</bold> Prof. Wael Abu Dayyih, Department of
              Pharmaceutical Chemistry, Faculty of Pharmacy, Mutah University, Al-Karak 61710, Jordan.
                              E-mail: <email xlink:href="maria.rossi@unimi.it">maria.rossi@unimi.it</email>
                          </corresp>
          </author-notes>
                    <pub-date pub-type="epub">
        <day>31</day>
        <month>03</month>
        <year>2025</year>
      </pub-date>
      <volume>16</volume>
      <issue>1</issue>
      <fpage>34</fpage>
      <lpage>42</lpage>
      <permissions>
        <copyright-statement>
          Copyright: &#x000a9; 2026 Archives of Pharmacy Practice
        </copyright-statement>
        <copyright-year>2026</copyright-year>
        <license>
          <ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/"
            specific-use="textmining" content-type="ccbyncsalicense">
            https://creativecommons.org/licenses/by-nc-sa/4.0/</ali:license_ref>
          <license-p>This is an open access journal, and articles are distributed under the terms of
            the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows
            others to remix, tweak, and build upon the work non-commercially, as long as appropriate
            credit is given and the new creations are licensed under the identical terms.</license-p>
        </license>
      </permissions>
      <abstract>
        <title>A<sc>BSTRACT</sc></title>
        <p>Digital pharmacy increasingly places algorithmic functions within medication workflows, yet the pharmacy workbench is still commonly treated as a physical workstation or software interface. This framing is insufficient because medication decisions emerge from interactions among patient context, prescription information, professional judgment, technical outputs, temporal pressures, communication, and organizational authority. This article proposes a sociotechnical architecture that reconceptualizes the pharmacy workbench as a human–AI coordination space rather than an automation endpoint. The architecture comprises six connected layers: patient context; prescription and medication information; bounded algorithmic functions; pharmacist judgment and action; coordination-state and temporal control; and escalation, governance, and learning. Algorithmic functions may detect, retrieve, prioritize, predict, summarize, explain, estimate uncertainty, or abstain, but their outputs remain distinct from medication decisions and professional authorization. Proposed coordination states make incomplete context, human–AI discordance, interruption, deferral, uncertainty, escalation, and closure visible rather than allowing them to remain implicit. Evaluation is organized across technical validity, clinical-task relevance, human–AI team performance, workflow fit, medication safety, equity, governance, external validity, and implementation sustainability. The architecture additionally requires task ownership, information provenance, resumption support, escalation acknowledgement, auditability, and controlled system change. It does not establish clinical effectiveness, reduced workload, improved medication safety, or deployment readiness. Its components, transition rules, and decision boundaries require empirical evaluation across pharmacy settings, medication tasks, professional roles, populations, and organizational conditions. The original contribution is an evidence-bounded architecture for studying and designing coordinated medication work without treating any model, alert, professional action, or data source as sufficient by itself.</p>
      </abstract>
      <kwd-group>
                <kwd>Digital pharmacy</kwd>
                <kwd>Artificial intelligence</kwd>
                <kwd>Pharmacy practice</kwd>
                <kwd>Medication safety</kwd>
                <kwd>Human–AI collaboration</kwd>
                <kwd>Clinical decision support</kwd>
              </kwd-group>
    </article-meta>
  </front>
</article>