Modern medicine cannot do without the use of new technologies, including nanotechnology. They make it possible to achieve significant improvements in the diagnosis and treatment of various diseases, as well as increase the effectiveness of prevention. In particular, in recent years, more and more attention has been paid to the use of silver, zinc, and copper nanoparticles in medicine. They have unique properties, such as antimicrobial, antiviral, and anti-inflammatory effects, which allows them to be used to fight various infections and inflammatory processes. This scientific paper examines the effect of medical treatment of a fresh wound with preparations based on silver nanoparticles and an alloy of copper and zinc in the example of laboratory rats. Visual observation of the wound healing process was carried out, as well as morphological and hematological parameters of blood serum were studied. During the experiment, it was found that the treatment of a fresh wound with a preparation based on silver nanoparticles led to the fastest wound healing. And treatment with a preparation based on copper and zinc alloy nanoparticles significantly reduced the recovery time. The toxicological safety of the use of both drugs has been proven.