Pain is a multidimensional sensation that arises from a physiologic and psychological response to an unpleasant experience. Pain is an alarm signal that causes an organism to pull away from potentially harmful stimuli, thereby protecting itself from potential damage. In most cases, it is associated with an injury or the possibility of an injury. Here we develop and carry out drug utilization evaluations concerning the analgesics and adjuvants in pain management. The analgesics and adjuvants were further classified to include in the program standards and criteria for the selected drugs and compared with the actual drug utilization. Cross-sectional, observational case study with 377 patients. Patients aged > 18 years and < 80 years experiencing pain were included in the study. Age < 18 years, > 80 years. Pregnant or lactating women were excluded from the study. Out of the total drugs (1362), total antibiotics prescribed were about 45 (3.30%). Among them, 35(2.6%) were prescribed in tablet form, (0.44%) were prescribed in injection form either i.v or i.m, 3(0.22%) were prescribed in powder form (gastolac sachets), 1 (0.07%) was prescribed in ointment form. Cefuroxime + clavulanic acid prescribed was the most commonly used 13 (0.95%). This study reveals a pattern of analgesic use that includes the administration of extensive oral analgesic preparations, a high generic naming of medications, and the appropriate use of these pharmaceuticals concerning the dosage strength, the frequency of treatment, and the duration of therapy.