TY  - JOUR
T1  - Simultaneous Determination of Oxazepam and Clomipramine by Continuous Wavelet and Derivative Transforms
A1  - Ruhollah Dastaran
A1  - Ali Sheibani
A1  - Masoud Reza Shishehbore
A1  - Hamid Saeedi-Sourck
JF  - Archives of Pharmacy Practice
JO  - Arch Pharm Pract
SN  - 2320-5210
Y1  - 2020
VL  - 11
IS  - 3
SP  - 63
EP  - 69
N2  - In this study, different types of mother wavelets from continuous wavelet transform (CWT) methods were proposed for simultaneous determination of oxazepam (OXA) and clomipramine (CLO) which are used to treat anxiety and major depressive disorder, respectively. For this purpose, the first derivative spectra obtained from overlapping absorption spectra were processed by various mother wavelets. Sym8, meyer, gaus5, and db6 were found to be appropriate for processing of the derivative UV spectra. To evaluate the performance of the proposed methods, the analytical validation parameters were investigated through the analysis of synthetic binary mixtures from two drugs. Calibration graphs in the linear concentration ranges of OXA (10-50 µg/mL) and CLO (12-25 µg/mL) were obtained (r>0.991). The capability of the proposed CWTs was also tested which gave good satisfactory results.
UR  - https://archivepp.com/article/simultaneous-determination-of-oxazepam-and-clomipramine-by-continuous-wavelet-and-derivative-transforms
ER  -