%0 Journal Article
%T Trends in Prescribing Antibiotic Therapy for Hospitalized Patients with Community-Acquired Pneumonia in Vietnam
%A Tuan Huynh Anh Phan
%A Thoai Dang Nguyen
%A Tram Thi Huyen Nguyen
%A Trung Quang Vo
%A Thao Thi Quy Le
%A Tro Van Chau
%A Sy Van Hoang
%J Archives of Pharmacy Practice
%@ 2320-5210
%D 2020
%V 11
%N 1
%P 14-21
%X Background: Community-acquired pneumonia (CAP) is a serious and common infectious disease with a high rate of morbidity and mortality among adults. Appropriate antibiotic treatment is therefore vital for reducing the disease incidence. Objective: This study aimed at determining the trends in antibiotic use in hospitalized patients with CAP. Methods: A retrospective study involving 479 medical records of hospitalized adults with CAP was undertaken at Tien Giang Central General Hospital in southern Vietnam during 2018–2019. Collected data included patient socio-demographic characteristics and administered antibiotic therapy. Results: Of the 479 CAP cases, 53.8% were female and more than half were aged 65 and above (average age 66.4±18.3 years). Cardiovascular diseases, gastrointestinal disorders, and pulmonary diseases were the most common morbidity of patients with CAP. Overall, 43% of the patients had used antibiotics before hospital admission. In the initial treatment, the most frequent single prescribed antibiotics were amoxicillin/clavulanic acid, ceftriaxone, and levofloxacin. Double combinations of the antibiotics in the initial treatment were used in 75.8% of the cases. Overall, 78.6% of the patients had good responses to the first-choice antibiotics. A negative association was noted between the pneumonia severity and antibiotic effectiveness (P
%U https://archivepp.com/article/trends-in-prescribing-antibiotic-therapy-for-hospitalized-patients-with-community-acquired-pneumonia-in-vietnam