TY - JOUR T1 - Trends in Prescribing Antibiotic Therapy for Hospitalized Patients with Community-Acquired Pneumonia in Vietnam A1 - Tuan Huynh Anh Phan A1 - Thoai Dang Nguyen A1 - Tram Thi Huyen Nguyen A1 - Trung Quang Vo A1 - Thao Thi Quy Le A1 - Tro Van Chau A1 - Sy Van Hoang JF - Archives of Pharmacy Practice JO - Arch Pharm Pract SN - 2320-5210 Y1 - 2020 VL - 11 IS - 1 SP - 14 EP - 21 N2 - Background: Community-acquired pneumonia (CAP) is a serious and common infectious disease with a high rate of morbidity and mortality among adults. Appropriate antibiotic treatment is therefore vital for reducing the disease incidence. Objective: This study aimed at determining the trends in antibiotic use in hospitalized patients with CAP. Methods: A retrospective study involving 479 medical records of hospitalized adults with CAP was undertaken at Tien Giang Central General Hospital in southern Vietnam during 2018–2019. Collected data included patient socio-demographic characteristics and administered antibiotic therapy. Results: Of the 479 CAP cases, 53.8% were female and more than half were aged 65 and above (average age 66.4±18.3 years). Cardiovascular diseases, gastrointestinal disorders, and pulmonary diseases were the most common morbidity of patients with CAP. Overall, 43% of the patients had used antibiotics before hospital admission. In the initial treatment, the most frequent single prescribed antibiotics were amoxicillin/clavulanic acid, ceftriaxone, and levofloxacin. Double combinations of the antibiotics in the initial treatment were used in 75.8% of the cases. Overall, 78.6% of the patients had good responses to the first-choice antibiotics. A negative association was noted between the pneumonia severity and antibiotic effectiveness (P UR - https://archivepp.com/article/trends-in-prescribing-antibiotic-therapy-for-hospitalized-patients-with-community-acquired-pneumonia-in-vietnam ER -