A Study on Surgical Prophylaxis of Antibiotics in Tertiary Care Hospital, Bangalore, India

To assess surgical prophylaxis of antibiotics in Tertiary Care Hospital, Bangalore, India. This was a prospective observational study carried out for in-patients in the department who underwent elective surgery; excludes nonselective or emergency surgery. The data collection form was prepared based on the requirements of the study which, included patients’ demographic details and their medical and mediation detail. The specific types of data necessary for the study were recorded for each patient encountered and entered directly into the form. A total of 150 inpatients were enrolled in the study and their prescriptions were studied for the data collection. All data were entered into a computer spreadsheet: Microsoft Excel and double-checked before the calculations were done. Computations of drug use patterns were carried out as described earlier. Following the literature review, the drug use evaluation for bronchial asthma from this study was compared with those obtained in previous similar studies.

The present study was carried out for six months in a tertiary care hospital in Bangalore. The mean age of the study participants was 27.08% years. A total of 96 males (45.83%) and females (54.17%) were studied. Cefuroxime (31.07%) was the most commonly prescribed followed by cefoperazone sulbactam (23.30%) and amoxicillin-clavulanic acid (16.50%). Fixed-dose combinations were also frequently used among which, meropenem+metronidazole (4.85%) was the most common combination used followed by the Piperacillin Tazobactam + Ciprofloxacin (3.88%) and cefuroxime+amikacin (2.91%). Cefuroxime plus a cefoperazone sulbactam agent was the preferred prescribed postoperative antimicrobial combination; single-agent prophylaxis was used in 95.92% as preoperative agents and 88.35% (91of96) as post-operative and combination agents were used in (4.08%) as preoperative agents and (11.65%) as postoperative in hospital. The study helped to make awareness creation on the antibiotic drugs and the rules were significant intercessions suggested for fitting careful antimicrobial use. We found the significance of all prescribers preserves the handiness of accessible antibiotics through the act of proper antimicrobial endorsing.