Archive \ Volume.12 2021 Issue 4

An Overview on Post-Cholecystectomy Syndrome Diagnostic & Management Approach

Ayman Ahmed Shaban Aldahshan, Ahmed Raafat Salamah, Noor Mohammed Fayoumi, Sami Awwadh Alkhudaydi, Mohammed Khaled M Alhijji, Qasem Adnan Abdulhameed Alnahwi, Atyaf Ahmad Balghsoon, Abdulmajid Omran Alomran, Saud Muhaisin Q Altalhi, Badriah Ibrahim Haqawi

Post-cholecystectomy syndrome can happen in 10% of patients after undergoing a cholecystectomy. Patients can present with extra-biliary and unrelated organic disorders that they may have been suffering from before the cholecystectomy. The various possible etiologies of post-cholecystectomy syndrome lead to a broad spectrum of treatment options with a variable success rate in reducing symptoms. This article aims to discuss a summary of the different etiologies of Post-cholecystectomy syndrome, the efficacy, and incidences of the different treatment options. PubMed database was used for articles selection, and the following keys were used in the mesh ((“Postcholecystectomy syndrome"[Mesh]) AND (“assessment”[Mesh]) OR (“Management"[Mesh])). In regards to the inclusion criteria, the articles were selected based on the inclusion of one of the following topics: Post Cholecystectomy syndrome, non-invasive assessment. Exclusion criteria were all other articles, which did not have one of these topics as their primary endpoint. Eitiologies of the postcholecystectomy syndrome are various, and many may be attributed to extra-biliary causes that can be present before the surgery. Early-onset of symptoms may require an early endoscopy to the upper gastrointestinal tract. Delayed patient presentations are most likely to retain biliary stones. Many of those patients will not have an identifiable cause. Thus, the treatment options will be limited for this group.

How to cite:
Aldahshan AAS, Salamah AR, Fayoumi NM, Alkhudaydi SA, Alhijji MKM, Alnahwi QAA, et al. An Overview on Post-Cholecystectomy Syndrome Diagnostic & Management Approach. Arch Pharm Pract. 2021;12(4):38-41.
Aldahshan, A. A. S., Salamah, A. R., Fayoumi, N. M., Alkhudaydi, S. A., Alhijji, M. K. M., Alnahwi, Q. A. A., Balghsoon, A. A., Alomran, A. O., Altalhi, S. M. Q., & Haqawi, B. I. (2021). An Overview on Post-Cholecystectomy Syndrome Diagnostic & Management Approach. Archives of Pharmacy Practice, 12(4), 38-41.

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1.        Zackria R, Lopez RA. Postcholecystectomy Syndrome. StatPearls. Treasure Island (FL): StatPearls Publishing. Copyright © 2021, StatPearls Publishing LLC. 2021.

2.        Schofer JM. Biliary causes of postcholecystectomy syndrome. J Emerg Med. 2010;39(4):406-10.

3.        Girometti R, Brondani G, Cereser L, Como G, Del Pin M, Bazzocchi M, et al. Post-cholecystectomy syndrome: spectrum of biliary findings at magnetic resonance cholangiopancreatography. Br J Radiol. 2010;83(988):351-61.

4.        Peterli R, Merki L, Schuppisser JP, Ackermann C, Herzog U, Tondelli P. Postcholecystectomy complaints one year after laparoscopic cholecystectomy. Results of a prospective study of 253 patients. Chirurg. 1998;69(1):55-60.

5.        Russello D, Di Stefano A, Scala R, Favetta A, Emmi S, Guastella T, et al. Does cholecystectomy always resolve biliary disease? Minerva Chir. 1997;52(12):1435-9.

6.        Freud M, Djaldetti M, De Vries A, Leffkowitz M. Postcholecystectomy syndrome: a survey of 114 patients after biliary tract surgery. Gastroenterologia. 1960;93(5):288-93.

7.        Redwan AA. Multidisciplinary approaches for management of postcholecystectomy problems (surgery, endoscopy, and percutaneous approaches). Surg Laparosc Endosc Percutan Tech. 2009;19(6):459-69.

8.        Isherwood J, Oakland K, Khanna A. A systematic review of the aetiology and management of post cholecystectomy syndrome. Surgeon. 2019;17(1):33-42.

9.        Abu Farsakh NA, Stietieh M, Abu Farsakh FA. The postcholecystectomy syndrome. A role for duodenogastric reflux. J Clin Gastroenterol. 1996;22(3):197-201.

10.      Sakai Y, Tsuyuguchi T, Ishihara T, Sugiyama H, Miyakawa K, Yukisawa S, et al. The usefulness of endoscopic transpapillary procedure in post-cholecystectomy bile duct stricture and post-cholecystectomy bile leakage. Hepato-gastroenterol. 2009;56(93):978-83.

11.      Phillips MR, Joseph M, Dellon ES, Grimm I, Farrell TM, Rupp CC. Surgical and endoscopic management of remnant cystic duct lithiasis after cholecystectomy--a case series. J Gastrointest Surg. 2014;18(7):1278-83.

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