Post-cholecystectomy syndrome can happen in 10% of patients after undergoing a cholecystectomy. Patients can present with extra-biliary and unrelated organic disorders that they may have been suffering from before the cholecystectomy. The various possible etiologies of post-cholecystectomy syndrome lead to a broad spectrum of treatment options with a variable success rate in reducing symptoms. This article aims to discuss a summary of the different etiologies of Post-cholecystectomy syndrome, the efficacy, and incidences of the different treatment options. PubMed database was used for articles selection, and the following keys were used in the mesh ((“Postcholecystectomy syndrome"[Mesh]) AND (“assessment”[Mesh]) OR (“Management"[Mesh])). In regards to the inclusion criteria, the articles were selected based on the inclusion of one of the following topics: Post Cholecystectomy syndrome, non-invasive assessment. Exclusion criteria were all other articles, which did not have one of these topics as their primary endpoint. Eitiologies of the postcholecystectomy syndrome are various, and many may be attributed to extra-biliary causes that can be present before the surgery. Early-onset of symptoms may require an early endoscopy to the upper gastrointestinal tract. Delayed patient presentations are most likely to retain biliary stones. Many of those patients will not have an identifiable cause. Thus, the treatment options will be limited for this group.
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