Objective: This study aimed to assess knowledge and attitudes towards pharmaceutical care service among hospital and community pharmacists working in Harar and Dire Dawa town, Eastern Ethiopia. Methodology: 78 pharmacists were included using a pretested self-administered questionnaire designed to carry out a cross-sectional survey. Results: The response rate was 97.5%, of which 58.9% were working in the hospitals while 41.1% were working in a community pharmacy setting. The majority of pharmacists (85.9%) were knowledgeable about pharmaceutical care. More than half of the pharmacists (52.6 %) had a positive attitude towards pharmaceutical care. Conclusion: Based on the current study, most pharmacists were knowledgeable about pharmaceutical care and had a positive attitude toward pharmaceutical care. Therefore, although the pharmaceutical care practice is a developing concept in Ethiopian settings, the results of this study were noticeable.
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