The aim of our study was to evaluate the effect of different etching times of hydrofluoric acid on the fracture strength of machinable lithium disilicate glass-ceramic (IPS e.max CAD). 80 IPS e.max CAD (5×5×2mm) specimens were divided into 5 groups (15 specimens in each group), using 5% Hydrofluoric acid (HF) to etch the groups (0 s, 20 s, 60 s, 120 s, 180 s). Then for 7 specimens of each group, silane was applied on the etched surface followed by a thin layer (0.1 mm) of resin cement. Fracture load was determined for all specimens using a universal testing machine with the use of a specially designed metal plate to hold the specimen during testing. All data were statistically analyzed using one-way ANOVA and paired t-test with a confidence interval of 95%. Etching IPS e.max CAD for 20 seconds did not decrease the fracture strength. While the other etching times showed a significant decrease in fracture strength with an increase in etching time. Resin cement significantly increased the fracture strength of each group.
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