Evaluation and Monitoring the Management of Urinary Tract Infection in the Department of Paediatric, Kempegowda Institute of Medical Sciences (Kims) Hospital and Research Centre, Bangalore, India

Objective: To assess various clinical manifestations of UTI in pediatric, to check for any ADR in drug utilization pattern of prescriptions. Methodology: 40 cases of suspected cases of UTI i.e. children below 18 yrs. of age with clinical features suggestive of UTI admitted to KIMS, Bangalore between December 2018 to May 2019 were studied. A detailed clinical history and physical examination was checked in case sheet. WHO classification and case definition were used. The data related to each of these cases was collected, compiled and analyzed. Result: The total number of 407 of all the infection cases that were admitted in hospital pediatric department during the period of January to June 2019 among them 40 cases were of UTI who satisfied the inclusion criteria and were included in the study among them 18 patients (45%) were female and remaining 22patients (55%) were male. We found the utilization pattern of antibiotics drug in 40 UTI patients with culture growth and without culture growth about 45 prescriptions were prescribed for antibiotic drugs out of which Cephalosporins 26 (57.77%) prescriptions were for Ceftriaxone which was highest and commonly used, Penicillin seven (15.55%) prescriptions were for Amoxicillin + Clavulanic Acid, frequency of Fluoroquinolones prescribed was five of which four (8.88%) prescriptions were for Ofloxacin and one (2.22%) prescription was for Norfloxacin, under Aminoglycosides three (6.66%) prescriptions were for Amikacin, under Nitrofuran one (2.22%) prescription was Nitrofurantoin, under Carbapenem one (2.22%) prescription was Meropenem, under Macrolide antibiotics one (2.22%) prescription was Azithromycin, under Oxazolidinone one (2.22%) prescription was Linezolid were least prescribed. Considering the distribution of the antibiotic drugs used in only 33 UTI patients with and without culture growth in this study population which Ceftriaxone (22) was highly used and the next common used were Amoxicillin + Clavulanic acid (5), and Ofloxacin (4), Amikacin (3) and remaining Nitrofurantoin, Meropenem, Linezolid, Azithromycin and Norfloxacin as mentioned before were the least. We identify Ceftriaxone (4), Amoxicillin + Clavulanic acid (2) were used in mixed infections patient in our study population where the outcome was excellent. Conclusion:  The clinical manifestation, examination finding, laboratory parameters. In our present study UTI without culture growth was most common presentation followed by UTI with growth culture. A focused history, detailed clinical examination and appropriate relevant investigations can aid for early diagnosis and treatment. Proper evaluation of the progress of the disease is a key in the management of disease.