Evaluation of Local Anesthesia Effect “Lidocaine +Epinephrine and Perilocaine s+Felypressin” on Blood Glucose level after Simple Extraction

Purpose: The aim of present study was to compare blood glucose level after simple dental extraction using local anesthesia (Lidocaine +epinephrine and Prilocaine +felypressin). Methods: This is a uni-blind randomized clinical trial study. Blood glucose level was measured in subjects who underwent a simple extraction in the posterior of the mandible. Subjects randomly divided into two groups. In the group 1, subjects received lidocaine and epinephrine (1.8 ml-1/80000) and lidocaine with felypressin (1.8 ml -0.03 IU/ml) in the group 2. Blood glucose level was measured 30 min before extraction and 30 min after it. Results: Sixty subjects were studied in two groups. Evaluation of the data did not show any significant change before and after extraction in each group. Comparison blood glucose level between two groups did not demonstrated any statistically difference. (P˃0.05) There was not any correlation between blood glucose change and age in each group. (P˃0.05). Conclusion: It seems exogenous epinephrine or felypressin may not affect blood glucose level after the simple tooth extraction. However, using local anesthesia with a higher volume of vasoconstrictors could be administrated cautiously.