Evaluation of the effect of oral vitamin E and omega 3 supplement on postmenopausal hot flashes

Background and objectives: Hot flashes and its complications are among the most annoying postmenopausal symptoms affecting the quality of life and mental state and mood. Anti-oxidants play an important role in the prevention and control of menopausal complications. In this study, the effect of oral vitamin E and omega 3 supplements on the hot flashes of postmenopausal women is evaluated. Method: This quasi-experimental interventional study was conducted on 80 postmenopausal women referring to gynecology and obstetrics clinic of Tamin-e-Ejtemaei Hospital of Zahedan in 2019. Patients I intervention group received and 850 mg capsule containing antioxidant supplement including omega 3 and Vitamin E. Demographic information questionnaires, personal information forms, and hot flashes severity weekly recording forms were used in this study for data collections. SPSS ver. 26 and chi-square, independent and paired T-test were used for data analysis and 0.05 was considered as significance level. Results: One week before the intervention, no significant difference in hot flashes severity was observed between the two groups. However, one week after the intervention, the hot flashes severity was significantly different between the two groups which further improved in the treatment period afterwards (P≤0.043). Conclusion: Findings of this study suggests that vitamin E and omega 3 supplement therapy is effective in the prevention of postmenopausal complications especially hot flashes severity and it can be used as a complementary and alternative medical methods in reducing menopause complications.