Treatment of wounds of various genesis (surgical, purulent, gunshot wounds) remains a pressing problem today. Along with the improvement of treatment methods, the methods of combat operations are also being improved. At the same time, the change of approaches to traditional methods of wound treatment promotes the growth of resistant forms of microorganisms. All these complicate the treatment of wounds and the course of the wound process. For the treatment of wounds using a wide arsenal of drugs (antibiotics, local antiseptics) in various dosage forms (ointments, sprays, powders, solutions). Traditionally, the main elements of complex local therapy of wounds are antimicrobial drugs on a hydrophilic basis, in particular on a polyethylene glycol base with high osmotic activity. Therefore, the development of combined drugs with prolonged action with osmotic activity, which can absorb exudate but does not lead to the formation of a dry crust on the wound surface, is relevant.