Introduction: The incidence of acute myocardial infarction (AMI) is high in Iran. AMI treatment is performed by thrombolysis or percutaneous coronary intervention (PCI). In cases of thrombolysis failure, rescue PCI is performed. It is hypothesized that right ventricular function is affected by AMI and might be a predictor of prognosis in AMI. The aim of this study was to compare right ventricular (RV) function in anterior AMI patients undergoing the three different treatment modalities. Materials and methods: This prospective cohort study was conducted on AMI patients who were referred to two tertiary hospitals in 2019 Iran. All subjects underwent echocardiography. Demographic characteristics as well as past medical history and echocardiographic findings were collected in a checklist. Data was analyzed by SPSS software version 23 using chi-square, ANOVA and Kruskal-Wallis. Results: A total of 70 subjects were recruited in this study (30 in primary PCI, 20 in rescue PCI,20 in thrombolysis responders). The mean age of the subjects was 54.89 ± 12.09 years old. There was no significant difference between treatment modalities in terms of age, sex, past medical history and smoking (p>0.05). Only a significant difference was observed in left ventricular end diastolic diameter (LVEDD) (p=0.035), RV fractional area change (FAC) (p=0.031) and right atrial volume (RAV) index between treatment groups. LVEDD was significantly higher in rescue PCI group compared to primary PCI group and FAC was significantly lower in rescue PCI group compared to thrombolysis responders and primary PCI groups and RAV index was significantly higher in rescue PCI group compared to the primary PCI. Conclusions: Right ventricular function is impaired to a greater extent in rescue PCI group. There is a need for further studies to evaluate these findings.
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