Since its first introduction, the usage of chlorhexidine has increased. The same holds for dental implants. Implant failures can happen, even with the stated high survival rates of implants. This systematic review's objective. This systematic study aims to assess how often post-operative infections and early implant failures may be prevented by using a chlorhexidine peri-operative rinse. The materials and techniques included a manual search of significant journals and reference lists of relevant publications and an electronic search of the literature using predetermined search parameters at specific databases (CENTRAL, Medline, Embase, Web of Science, Scopus, ScienceDirect). After duplicates were eliminated, the 251 records found during the search were reduced to 108. Eleven full-text papers were acquired after titles and abstracts were screened. For this systematic review, one article met the eligibility requirements. There were 595 individuals in the population; 325 (the Treatment group) received a mouthwash containing 0.12% chlorhexidine prior to implant insertion surgery, whereas the Control group (325) received no peri-operative rinse. 5.8% of the treatment group and 9.3% of the control group had infectious problems. When chlorhexidine was utilized as a peri-operative rinse, the chance of infection problems after implant insertion was shown to be 36% lower, with a calculated relative risk of 0.63. In summary, very little evidence suggests that using a mouthwash containing chlorhexidine before surgery would lower the chance of infection after surgery. To enable the development of compelling recommendations based on evidence, further study in this area is required.
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