Archive \ Volume.11 2020 Issue 1

Trends in Prescribing Antibiotic Therapy for Hospitalized Patients with Community-Acquired Pneumonia in Vietnam

, , , , , ,
  1. Tay Do University, Can Tho City 900000, Vietnam.
  2. Pham Ngoc Thach University of Medicine, Ho Chi Minh City 700000, Vietnam.
  3. Ear-Nose-Throat Hospital in Ho Chi Minh City, Ho Chi Minh City 700000, Vietnam.
  4. University of Medicine and Pharmacy at Ho Chi Minh City, Ho Chi Minh City 700000, Vietnam.

Abstract

Background: Community-acquired pneumonia (CAP) is a serious and common infectious disease with a high rate of morbidity and mortality among adults. Appropriate antibiotic treatment is therefore vital for reducing the disease incidence. Objective: This study aimed at determining the trends in antibiotic use in hospitalized patients with CAP. Methods: A retrospective study involving 479 medical records of hospitalized adults with CAP was undertaken at Tien Giang Central General Hospital in southern Vietnam during 2018–2019. Collected data included patient socio-demographic characteristics and administered antibiotic therapy. Results: Of the 479 CAP cases, 53.8% were female and more than half were aged 65 and above (average age 66.4±18.3 years). Cardiovascular diseases, gastrointestinal disorders, and pulmonary diseases were the most common morbidity of patients with CAP. Overall, 43% of the patients had used antibiotics before hospital admission. In the initial treatment, the most frequent single prescribed antibiotics were amoxicillin/clavulanic acid, ceftriaxone, and levofloxacin. Double combinations of the antibiotics in the initial treatment were used in 75.8% of the cases. Overall, 78.6% of the patients had good responses to the first-choice antibiotics. A negative association was noted between the pneumonia severity and antibiotic effectiveness (P<0.05). Conclusions: Although the initial treatment was successful in the majority of hospitalized patients with CAP, the severity of pneumonia still required attention from healthcare professionals to improve the effectiveness of the treatment.



How to cite:
Vancouver
Phan THA, Nguyen TD, Nguyen TTH, Vo TQ, Le TTQ, Chau TV, et al. Trends in Prescribing Antibiotic Therapy for Hospitalized Patients with Community-Acquired Pneumonia in Vietnam. Arch Pharm Pract. 2020;11(1):14-21.
APA
Phan, T. H. A., Nguyen, T. D., Nguyen, T. T. H., Vo, T. Q., Le, T. T. Q., Chau, T. V., & Hoang, S. V. (2020). Trends in Prescribing Antibiotic Therapy for Hospitalized Patients with Community-Acquired Pneumonia in Vietnam. Archives of Pharmacy Practice, 11(1), 14-21.

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