Archive \ Volume.2 2011 Issue 1

Studies on the Anti-Inflammatory and Analgesic Efficacy of Saraca asoca in Laboratory Animals

Mohammad Kawsar Sharif , M Hossain1 , M Erfan Uddin , ATM Omar Farooq , M Ashraful Islam , Mohammad Manzur Sharif
Abstract

Objective: This research was focused on the qualitative and quantitative evaluation of anti-inflammatory and analgesic effects of Saraca asoca in laboratory animals and whether these effects were of any statistical significance. Materials and methods: Carrageenan-induced Hind Paw Edema test in long evans rat was the experiment for antiinflammatory activity of the ethanolic extract of Saraca asoca while hot plate test was carried out to assess its analgesic activity in swiss albino mice. Result: The experimental activities for the ethanolic extract of Asoca saraca exhibited statistically significant (p<0.05) antiinflammatory activity in Carrageenan-induced Hind Paw Edema in long evans rat. Conclusion: In conclusion, these observations provide evidence and possible mechanisms of action for the antiinflammatory and probable analgesic properties of bark of Saraca asoca claimed in Ayurveda medicine. Further studies should be undertaken to correlate the pharmacological activitiesObjective: This research was focused on the qualitative and quantitative evaluation of anti-inflammatory and analgesic effects of Saraca asoca in laboratory animals and whether these effects were of any statistical significance. Materials and methods: Carrageenan-induced Hind Paw Edema test in long evans rat was the experiment for antiinflammatory activity of the ethanolic extract of Saraca asoca while hot plate test was carried out to assess its analgesic activity in swiss albino mice. Result: The experimental activities for the ethanolic extract of Asoca saraca exhibited statistically significant (p<0.05) antiinflammatory activity in Carrageenan-induced Hind Paw Edema in long evans rat. Conclusion: In conclusion, these observations provide evidence and possible mechanisms of action for the antiinflammatory and probable analgesic properties of bark of Saraca asoca claimed in Ayurveda medicine. Further studies should be undertaken to correlate the pharmacological activities