Hyperthyroidism is specified by the mass manufacture of thyroid hormone and/or release from the thyroid gland. Thyrotoxicosis is a sickness in which the impacts of an inappropriate enhancement in thyroid hormone on tissues lead to difficulties and systemic symptoms. High thyroid hormone levels cause a hyper metabolic condition that induces multiple systemic manifestations. Managing hyperthyroidism cases is considered a difficult challenge because of the variety of the underlying causes and the variety of the management options. An assessment of publicized literature discussing hyperthyroidism and to equip an adequate analysis of hyperthyroidism, its diagnosis, and management. The following keys were used in the mesh ((“hyperthyroidism"[Mesh]) AND (“management” [Mesh]) OR (“evaluation"[Mesh])). And PubMed database was used for articles selection. Hyperthyroidism is a condition that is commonly overlooked. Maintaining a high suspicion index is important for the primary healthcare physician. Treatment suggestions are based on characteristics diversity, including underlying reason, patient age, disease severity, and comorbidity. The major treatment options are ant thyroid medications (thionamides), surgery, and radioactive iodine. All methods had equal quality of life parameters, but generally, radioiodine was the most cost-effective.
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