Pregnancy profoundly affects several aspects of a woman's life in today's society. Mental and physical health have different incidences among pregnant women, and they also have a higher risk for certain psychological conditions. Starting from the group's psychological profiler and clinical psychologist, we chose a set of questioners and analyzed a group of pregnant women enrolled in the pregnancy follow-up program by their family doctor/G.P. Starting from the test-retest method, we analyzed pregnancy from several psychological perspectives (depression, anxiety, and self-esteem) and set out to determine these fluctuations by trimester of pregnancy. We chose the test and retest method to establish the initial level of depression, anxiety, and self-esteem and applied the questionnaires in each trimester, trying to apply them in the midweek (+/- 1 week) for each participant. All tests and questions indicated statistically significant increases of a worrying magnitude. An immediate priority of the scientific community should be collecting high-quality data on the mental health effects of the COVID-19 pandemic across the whole population and especially vulnerable groups such as pregnant women who were presented in this study.