Synthesis of carbohydrate esters and investigation reaction of Phosphoryl chloride from anomeric position of Per-Acetylated Carbohydrates

Carbohydrates are a large class of organic compounds which can be found in the structure of living organisms. They are  major  energy source for  both plants, and  animals that  play an important  role in feeding the living organisms. Likewise, these compounds are quintessential reactions of ATP, RNA and DNA. The anomeric position of carbohydrates prepare them to chemical reactions.in this paper, Carbohydrate esters were prepared by acetic anhydride in the presence of sodium acetate and Lewis acid. Then selective anomeric position with MgO/MeOH was deacetylatd, then was reacted with phosphoryl chloride, In another method, the acetylated carbohydrates were reacted directly with phosphoryl chloride without deacetylation anomeric position. In two different situations, the same product was obtained. Phosphate ester carbohydrate was identified by ¹³P-NMR technique.